化工社化工社 化学情報印刷レポート · 研究参考用
Acetic Acid → 3,5-Dihydroxyadamantane-1-carboxylic acid
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Acetic Acid | HCID 176 | — |
| 反応物 | Oxygen | HCID 977 | — |
| 反応物 | 1,3-Adamantanediol | HCID 573829 | — |
| 反応物 | HCID 178418416 | HCID 178418416 | — |
| 生成物 | 3,5-Dihydroxyadamantane-1-carboxylic acid | HCID 12010647 | 80% |
反応手順
A reactor was charged with 10 mmole of 1,3-adamantanediol, 1 mmole of NHPI, 0.005 mmole of Co(AA)2 and 25 mL of acetic acid, then equipped with a gas bag of mixed gas (a mixed gas of 2 L of carbon monoxide and 0. 5 L of oxygen; pressure: 5 kg/cm ). The resultant mixture was stirred for 6 hours at 60° C. to give 1-carboxy-3,5-adamantanediol (yield 80%). The conversion of 1,3-adamantanediol was 99%.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US06392104B1 |
| 出典データセット | uspto-grants-2002_05 |
| ORD ID | ord-bf397c7510b14856b2320708b49b5837 |
| 出典メモ | uspto-grants-2002_05 |