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Ethanol → 3-Aminoquinoline
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Ethanol | HCID 702 | — |
| 反応物 | Ethyl Acetate | HCID 8857 | — |
| 反応物 | Stannous Chloride | HCID 24479 | — |
| 反応物 | 3-Nitroquinoline | HCID 25551 | — |
| 触媒 | Iron | HCID 23925 | — |
| 触媒 | Palladium | HCID 23938 | — |
| 触媒 | Zinc | HCID 23994 | — |
| 触媒 | Platinum oxide (PtO) | HCID 82844 | — |
| 溶媒 | Acetic Acid | HCID 176 | — |
| 溶媒 | Methanol | HCID 887 | — |
| 溶媒 | Tetrahydrofuran | HCID 8028 | — |
| 生成物 | 3-Aminoquinoline | HCID 11375 | — |
反応手順
The 3-nitroquinoline derivative of the formula (c) is then catalytically reduced in an inert solvent such as ethanol, ethyl acetate, methanol or THF, using platinum oxide or palladium/carbon, or reduced by iron or zinc and acetic acid or tin (II) chloride, to give the 3-aminoquinoline derivative of the formula (d).
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US05693651 |
| 出典データセット | uspto-grants-1997_12 |
| ORD ID | ord-8821263ce0054d48b38ee0adbffc7235 |
| 出典メモ | uspto-grants-1997_12 |