3-Nitro-7-(5-ethyl-2-pyridylmethoxy)quinoline → 3-Amino-7-(5-ethyl-2-pyridylmethoxy)quinoline

HRID 1938344ノート

反応式

HRID 1938344 の反応式
[N+:1]([C:4]1[CH:5]=[N:6][C:7]2[C:12]([CH:13]=1)=[CH:11][CH:10]=[C:9]([O:14][CH2:15][C:16]1[CH:21]=[CH:20][C:19]([CH2:22][CH3:23])=[CH:18][N:17]=1)[CH:8]=2)([O-])=O>C(O)C.[Pt]=O>[NH2:1][C:4]1[CH:5]=[N:6][C:7]2[C:12]([CH:13]=1)=[CH:11][CH:10]=[C:9]([O:14][CH2:15][C:16]1[CH:21]=[CH:20][C:19]([CH2:22][CH3:23])=[CH:18][N:17]=1)[CH:8]=2

参加物

4

反応物 1

HCID 214692903-Nitro-7-(5-ethyl-2-pyridylmethoxy)quinoline

生成物 1

HCID 214692773-Amino-7-(5-ethyl-2-pyridylmethoxy)quinoline

試薬・触媒・溶媒 2

HCID 82844Platinum oxide (PtO)触媒HCID 702Ethanol溶媒

実験手順

In ethanol (20 mL) was suspended 3-nitro-7-(5-ethyl-2-pyridylmethoxy)quinoline (700 mg, 2.26 mmol.), and to the suspension was added platinum oxide (80 mg). Then, catalytic reduction was performed for 3 hours. After the completion of reaction was confirmed, the reaction mixture was filtered over Celite®, and the filtrate was placed under reduced pressure to give the desired compound as residual oil in a quantitative yield.

後処理

  1. customAfter the completion of reaction
  2. filtrationthe reaction mixture was filtered over Celite®

出典と根拠

ORDレコード
ord-6cdf47ffa16846fcb5a9aa3de90c89dd
出典データセット
uspto-grants-1997_12
特許番号
US05693651

反応ノート

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