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HRID 1939283作成日:2026年10月27日

1-Isothiocyanato-3-(trifluoromethyl)benzene → N-(3-(trifluoromethyl)phenyl)-N'-(2-methoxy-5-(trifluoromethyl)phenyl) thiourea

https://huagongshe.com/reaction/1939283

反応式

関与物質

役割名称HCID仕込み量
反応物1-Isothiocyanato-3-(trifluoromethyl)benzeneHCID 137232—
反応物2-Methoxy-5-(trifluoromethyl)anilineHCID 600637—
溶媒TolueneHCID 1140—
生成物N-(3-(trifluoromethyl)phenyl)-N'-(2-methoxy-5-(trifluoromethyl)phenyl) thioureaHCID 5419792951%

反応手順

3-(trifluoromethyl)phenyl isothiocyanate in toluene (0.76 ml, 5.0 mmol) was added to a solution of 2-methoxy-5-(trifluoromethyl)aniline in toluene (10 ml). The resulting reaction mixture was stirred at RT overnight and the product was subsequently filtered off. 1.00 g (51%) of the title compound was isolated.

情報源と証拠

DOI10.6084/m9.figshare.5104873.v1
特許番号US05696138
出典データセットuspto-grants-1997_12
ORD IDord-0da55e70336c4445bca4d21c00860d8f
出典メモuspto-grants-1997_12