Ethanol → 2,4-D-ethyl
反応式
OS(O)(=O)=O.[Cl:6][C:7]1[CH:17]=[C:16]([Cl:18])[CH:15]=[CH:14][C:8]=1[O:9][CH2:10][C:11]([OH:13])=[O:12].[CH2:19](O)[CH3:20]>>[Cl:6][C:7]1[CH:17]=[C:16]([Cl:18])[CH:15]=[CH:14][C:8]=1[O:9][CH2:10][C:11]([O:13][CH2:19][CH3:20])=[O:12]参加物
4
実験手順
1.3 g (14 mmol) of H2SO4 were added to 15.0 g (68 mmol) of 2,4-dichlorophenoxyacetic acid in 20 ml of ethanol, and the mixture was refluxed for 5 hours. The mixture was subsequently concentrated in vacuo, the residue was poured into 100 ml of ice-water, the organic phase was separated off, and the aqueous phase was extracted using ether. The combined organic phases were washed using 2N Na2CO3 solution and water, dried over magnesium sulfate and concentrated. 8.9 g (53% of theory) of ethyl 2,4-dichlorophenoxyacetate were obtained as a colorless oil.
後処理
- temperaturethe mixture was refluxed for 5 hours
- concentrationThe mixture was subsequently concentrated in vacuo
- additionthe residue was poured into 100 ml of ice-water
- customthe organic phase was separated off
- extractionthe aqueous phase was extracted
- washThe combined organic phases were washed
- dry with materialdried over magnesium sulfate
- concentrationconcentrated
出典と根拠
- ORDレコード
- ord-33504bd217a745aa92858c5740299f06
- 出典データセット
- uspto-grants-1997_12
- 特許番号
- US05698539
反応ノート
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