HCID 9798400、化合物 → HCID 18977165、化合物

HRID 1939925ノート

反応式

HRID 1939925 の反応式
[N:1]1[CH:6]=[CH:5][CH:4]=[C:3]([C:7]([NH:9][CH2:10][CH2:11][CH2:12][CH2:13][C:14]2[CH:19]=[CH:18][C:17]([C:20]3[CH:21]=[CH:22][C:23](=[O:26])[NH:24][N:25]=3)=[CH:16][CH:15]=2)=[O:8])[CH:2]=1.[ClH:27].C(O)C>C(O)C>[ClH:27].[N:1]1[CH:6]=[CH:5][CH:4]=[C:3]([C:7]([NH:9][CH2:10][CH2:11][CH2:12][CH2:13][C:14]2[CH:19]=[CH:18][C:17]([C:20]3[CH:21]=[CH:22][C:23](=[O:26])[NH:24][N:25]=3)=[CH:16][CH:15]=2)=[O:8])[CH:2]=1

参加物

4

反応物 2

HCID 9798400HCID 9798400、化合物HCID 21887872Ethanol hydrochloride

生成物 1

HCID 18977165HCID 18977165、化合物

試薬・触媒・溶媒 1

HCID 702Ethanol溶媒

実験手順

In hot ethanol (180 ml) was dissolved 8.9 g of 6-[4-(4-(pyridin-3-ylcarbonylamino)butyl)phenyl]pyridazin-3(2H)-one. A 18 % hydrochloric acid-ethanol solution (10 ml) was added to the solution, and the mixture was left to stand at room temperature. Precipitated crystal was collected by filtration and washed with cold ethanol to obtain 9.3 g of 6-[4-(4-(pyridin-3-ylcarbonylamino)butyl)phenyl]pyridazin-3(2H)-one hydrochloride.

後処理

  1. waitthe mixture was left
  2. customto stand at room temperature
  3. customPrecipitated crystal
  4. filtrationwas collected by filtration
  5. washwashed with cold ethanol

出典と根拠

ORDレコード
ord-cc715010b6cf41a98e1adf14ef5c7b73
出典データセット
uspto-grants-1997_12
特許番号
US05698554

反応ノート

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