関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|
| 反応物 | Thionyl Chloride | HCID 24386 | — |
| 反応物 | 2-(4-Tolyl)propanoic acid | HCID 150866 | — |
| 生成物 | 2-(4-Methylphenyl)propionyl chloride | HCID 14946079 | 100.1% |
反応手順
160.65 g (1.35 mol) of thionyl chloride are placed in a 1 liter three-necked flask fitted with a mechanical stirrer and a condenser. 164.2 g (0.9 mol) of p-methylphenylpropionic acid are added little by little thereto at room temperature. After 4 hours, the reaction is terminated by heating at 60° C. for 1 hour. Excess SOCl2 is removed by distillation/n vacuo. In that manner 164.5 g of p-methylphenylpropionic acid chloride are obtained.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| 特許番号 | US05703074 |
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| 出典データセット | uspto-grants-1997_12 |
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| ORD ID | ord-980b86e2f0634cf3904e06b1c9e828f0 |
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| 出典メモ | uspto-grants-1997_12 |
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