4-Heptanol, 1,1,1,7,7,7-hexafluoro- → 1,1,1,7,7,7-Hexafluoro-4-heptanone

HRID 1942309ノート

反応式

HRID 1942309 の反応式
[F:1][C:2]([F:14])([F:13])[CH2:3][CH2:4][CH:5]([OH:12])[CH2:6][CH2:7][C:8]([F:11])([F:10])[F:9].[Cr](Cl)([O-])(=O)=O.[NH+]1C=CC=CC=1>C(Cl)Cl>[F:1][C:2]([F:13])([F:14])[CH2:3][CH2:4][C:5](=[O:12])[CH2:6][CH2:7][C:8]([F:10])([F:11])[F:9]

参加物

4

反応物 2

HCID 538257994-Heptanol, 1,1,1,7,7,7-hexafluoro-HCID 178418287HCID 178418287、化合物2 回

生成物 1

HCID 5805611,1,1,7,7,7-Hexafluoro-4-heptanone

試薬・触媒・溶媒 1

HCID 6344Dichloromethane溶媒

実験手順

1,1,1,7,7,7-Hexafluoroheptan-4-ol (1.4 g, 6.25 mmol) was dissolved in CH2Cl2 (12 mL) and pyridinium chlorochromate (PCC) (1.48 g, 6.87 mmol) was added. The mixture was stirred for 4 h. Additional PCC (800 mg) was added and the mixture stirred for 1 h. The mixture was filtered through celite and silica, washing with DCM. The resulting pale yellow solution was evaporated at room temperature to afford the title compound.

後処理

  1. stirringthe mixture stirred for 1 h
  2. filtrationThe mixture was filtered through celite and silica
  3. washwashing with DCM
  4. customThe resulting pale yellow solution was evaporated at room temperature

出典と根拠

ORDレコード
ord-f3cbb7be50b041a6a8f31574d5bc39fc
出典データセット
uspto-grants-2013_03
特許番号
US08389547B2

反応ノート

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