Propyl-(4,5,6,7-tetrahydro-benzothiazol-6-yl)-amine → Naphthalene-2-carboxylic acid {2-[ethyl-(4,5,6,7-tetrahydro-benzothiazol-6-yl)-amino]-ethyl}-amide

HRID 1942367ノート

反応式

HRID 1942367 の反応式
O=[CH:2][CH2:3][NH:4][C:5]([C:7]1[CH:16]=[CH:15][C:14]2[C:9](=[CH:10][CH:11]=[CH:12][CH:13]=2)[CH:8]=1)=[O:6].[CH2:17]([NH:20][CH:21]1[CH2:29][CH2:28][C:24]2[N:25]=[CH:26][S:27][C:23]=2[CH2:22]1)[CH2:18]C>>[CH2:17]([N:20]([CH:21]1[CH2:29][CH2:28][C:24]2[N:25]=[CH:26][S:27][C:23]=2[CH2:22]1)[CH2:2][CH2:3][NH:4][C:5]([C:7]1[CH:16]=[CH:15][C:14]2[C:9](=[CH:10][CH:11]=[CH:12][CH:13]=2)[CH:8]=1)=[O:6])[CH3:18]

参加物

3

反応物 2

HCID 18705889Propyl-(4,5,6,7-tetrahydro-benzothiazol-6-yl)-amineHCID 86651307Naphthalene-2-carboxylic acid (2-oxo-ethyl)-amide

生成物 1

HCID 66937429Naphthalene-2-carboxylic acid {2-[ethyl-(4,5,6,7-tetrahydro-benzothiazol-6-yl)-amino]-ethyl}-amide収率 34%

実験手順

Compound 32 is prepared from 32B and 1C as described for 1. The salt of oxalic acid is crystallized from ethanol/diethylether.

後処理

  1. customThe salt of oxalic acid is crystallized from ethanol/diethylether

出典と根拠

ORDレコード
ord-bf2704b81fba4cb284d863ce3ad89390
出典データセット
uspto-grants-2013_03
特許番号
US08389555B2

反応ノート

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