1,2,3,4-Tetrahydronaphthalene-2-carbonyl chloride → 4-{[Propyl-(4,5,6,7-tetrahydro-benzothiazol-6-yl)-amino]-methyl}-benzoyl chloride

HRID 1942398ノート

反応式

HRID 1942398 の反応式
[CH2:1]([N:4]([CH2:14][C:15]1[CH:23]=[CH:22][C:18]([C:19](O)=[O:20])=[CH:17][CH:16]=1)[CH:5]1[CH2:13][CH2:12][C:8]2[N:9]=[CH:10][S:11][C:7]=2[CH2:6]1)[CH2:2][CH3:3].C1C2C(=CC=CC=2)CCC1C([Cl:36])=O>>[CH2:1]([N:4]([CH2:14][C:15]1[CH:23]=[CH:22][C:18]([C:19]([Cl:36])=[O:20])=[CH:17][CH:16]=1)[CH:5]1[CH2:13][CH2:12][C:8]2[N:9]=[CH:10][S:11][C:7]=2[CH2:6]1)[CH2:2][CH3:3]

参加物

3

反応物 2

HCID 156707901,2,3,4-Tetrahydronaphthalene-2-carbonyl chlorideHCID 669374084-{[Propyl-(4,5,6,7-tetrahydro-benzothiazol-6-yl)-amino]-methyl}-benzoic acid

生成物 1

HCID 866513144-{[Propyl-(4,5,6,7-tetrahydro-benzothiazol-6-yl)-amino]-methyl}-benzoyl chloride

実験手順

4-{[Propyl-(4,5,6,7-tetrahydro-benzothiazol-6-yl)-amino]-methyl}-benzoyl chloride (42C) is prepared from 42B as described for 23A. The crude product is obtained in almost quantitative yield.

出典と根拠

ORDレコード
ord-92e9c67b21054493a902f4115887bca1
出典データセット
uspto-grants-2013_03
特許番号
US08389555B2

反応ノート

読み込み中…