2-(Ethoxymethylene)propanedinitrile → 3.7-diphenyl-3H-imidazo[4,5-b]pyridine
反応式
[C:1]1([NH:7][C:8]2[C:13]([NH2:14])=[C:12]([C:15]3[CH:20]=[CH:19][CH:18]=[CH:17][CH:16]=3)[CH:11]=[CH:10][N:9]=2)[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.[CH2:21](OC=C(C#N)C#N)C>C(O)(C)C>[C:1]1([N:7]2[C:8]3=[N:9][CH:10]=[CH:11][C:12]([C:15]4[CH:16]=[CH:17][CH:18]=[CH:19][CH:20]=4)=[C:13]3[N:14]=[CH:21]2)[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1参加物
4
実験手順
0.70 mol of N2,4-diphenylpyridine-2,3-diamine and 2.56 mol of ethoxymethylene malononitrile were added in 10 ml of isopropanol, and refluxed for 6 hours. The solution was removed and was purified by using column chromatography to thereby produce a solid crystalline product at a yield of 75%.
後処理
- temperaturerefluxed for 6 hours
- customThe solution was removed
- customwas purified
- customto thereby produce a solid crystalline product at a yield of 75%
出典と根拠
- ORDレコード
- ord-40e8e1092dad4e8facb4458154b49562
- 出典データセット
- uspto-grants-2010_06
- 特許番号
- US07745020B2
反応ノート
読み込み中…