6-Amino-1-hexanol → 6-[[3-[(6-Hydroxyhexyl)carbamoyl]phenyl]sulfonyl]-4-[(3-methoxyphenyl)amino]-8-methylquinoline-3-carboxamide
反応式
OCCCC[CH2:6][CH2:7][CH2:8][CH2:9][NH:10][C:11]([C:13]1[CH:14]=[C:15]([S:19]([C:22]2[CH:23]=[C:24]3[C:29](=[C:30]([CH3:32])[CH:31]=2)[N:28]=[CH:27][C:26]([C:33]([NH2:35])=[O:34])=[C:25]3[NH:36][C:37]2[CH:42]=[CH:41][CH:40]=[C:39]([O:43][CH3:44])[CH:38]=2)(=[O:21])=[O:20])[CH:16]=[CH:17][CH:18]=1)=[O:12].NCCCC[CH2:50][CH2:51][OH:52]>>[OH:52][CH2:51][CH2:50][CH2:6][CH2:7][CH2:8][CH2:9][NH:10][C:11]([C:13]1[CH:14]=[C:15]([S:19]([C:22]2[CH:23]=[C:24]3[C:29](=[C:30]([CH3:32])[CH:31]=2)[N:28]=[CH:27][C:26]([C:33]([NH2:35])=[O:34])=[C:25]3[NH:36][C:37]2[CH:42]=[CH:41][CH:40]=[C:39]([O:43][CH3:44])[CH:38]=2)(=[O:21])=[O:20])[CH:16]=[CH:17][CH:18]=1)=[O:12]参加物
3
実験手順
The title compound was synthesized in a manner analogous to that described for Intermediate 70, using 6-aminohexanol in place of 8-aminooctanol. ES/MS calcd. for C31H35N4O6S+ 591.2. Found m/z=591.3 (M+H)+.
出典と根拠
- ORDレコード
- ord-d7220b55e3654025bad3f5256c8a8d76
- 出典データセット
- uspto-grants-2013_03