関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|
| 反応物 | Thionyl Chloride | HCID 24386 | — |
| 反応物 | 2(4-Biphenyl)propionic acid | HCID 3082434 | — |
| 生成物 | 3-(Biphenyl-4-yl)propanoyl chloride | HCID 59607563 | 101% |
反応手順
A mixture of 3-(4-biphenylyl)propionic acid (5 g, 22.10 mmol) and SOCl2 (4.03 ml, 55.2 mmol) is refluxed under nitrogen at 85° C. for 1.5 hour. The reaction mixture is concentrated under reduced pressure to give 3-(biphenyl-4-yl)propanoyl chloride (5.46 g). The material is used in the next step without further purification.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 特許番号 | US08394853B2 |
|---|
| 出典データセット | uspto-grants-2013_03 |
|---|
| ORD ID | ord-19230151c3814bda98578d458c6fa63d |
|---|
| 出典メモ | uspto-grants-2013_03 |
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