化工社化工社 化学情報印刷レポート · 研究参考用
N-(2-methylpropyl)cyclopentanamine → N-[4-(aminosulfonyl)-2-methylphenyl]-6-[cyclopentyl(isobutyl)amino]pyrimidine-4-carboxamide
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | N-(2-methylpropyl)cyclopentanamine | HCID 28428761 | — |
| 反応物 | 6-Chloro-pyrimidine-4-carboxylic acid (2-methyl-4-sulfamoyl-phenyl)amide | HCID 59447056 | — |
| 生成物 | N-[4-(aminosulfonyl)-2-methylphenyl]-6-[cyclopentyl(isobutyl)amino]pyrimidine-4-carboxamide | HCID 25182906 | 80% |
反応手順
Following the general method as outlined in Example 20, starting from 6-chloro-pyrimidine-4-carboxylic acid (2-methyl-4-sulfamoyl-phenyl)-amide (Intermediate 17) and cyclopentyl-isobutyl-amine (Intermediate 27), the title compound was obtained as a white solid in 80% yield.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US08399448B2 |
| 出典データセット | uspto-grants-2013_03 |
| ORD ID | ord-c19df2d7c12449fab918322b8cc518e6 |
| 出典メモ | uspto-grants-2013_03 |