Diethyl(4-nitrophenyl)phosphonate → P-(4-Nitrophenyl)phosphonic acid

HRID 1947793ノート

反応式

HRID 1947793 の反応式
C([O:3][P:4]([C:9]1[CH:14]=[CH:13][C:12]([N+:15]([O-:17])=[O:16])=[CH:11][CH:10]=1)(=[O:8])[O:5]CC)C>Cl>[N+:15]([C:12]1[CH:11]=[CH:10][C:9]([P:4](=[O:3])([OH:5])[OH:8])=[CH:14][CH:13]=1)([O-:17])=[O:16]

参加物

3

反応物 1

HCID 284865Diethyl(4-nitrophenyl)phosphonate

生成物 1

HCID 196997P-(4-Nitrophenyl)phosphonic acid収率 100%

試薬・触媒・溶媒 1

HCID 313Hydrochloric Acid溶媒

実験手順

A solution of diethyl(4-nitrophenyl)phosphonate (60 g, 230 mmol) in 250 mL of concentrated HCl (aq) was stirred at reflux overnight. The excess HCl was removed under reduced pressure and the product used in further chemistries without purification (46.8 g, yield: 100%).

後処理

  1. temperatureat reflux overnight
  2. customThe excess HCl was removed under reduced pressure
  3. customthe product used in further chemistries without purification (46.8 g, yield: 100%)

出典と根拠

ORDレコード
ord-3b0357372e794db29131a38f1aeb1aa9
出典データセット
uspto-grants-2013_03
特許番号
US08399433B2

反応ノート

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