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2-Methoxybenzaldehyde → 4-(2,5-Difluoro-phenyl)-N2-(2-methoxy-benzyl)-N6-pyridin-3-ylmethyl-quinoline-2,6-diamine
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | 2-Methoxybenzaldehyde | HCID 8658 | — |
| 反応物 | 3-Pyridinemethanamine | HCID 31018 | — |
| 反応物 | (2,5-Difluorophenyl)boronic acid | HCID 2734335 | — |
| 反応物 | HCID 178507935 | HCID 178507935 | — |
| 生成物 | 4-(2,5-Difluoro-phenyl)-N2-(2-methoxy-benzyl)-N6-pyridin-3-ylmethyl-quinoline-2,6-diamine | HCID 25235616 | — |
反応手順
The title compound, MS: m/e=483.5 (M+H+), was prepared in accordance with the general method of example 30 from 2-amino-6-chloro-4-hydroxyquinoline (CAS 64319-84-2), 2,5-difluorophenylboronic acid, 2-methoxybenzaldehyde and 3-picolylamine.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US08399674B2 |
| 出典データセット | uspto-grants-2013_03 |
| ORD ID | ord-29ab4f83fbdb4220a42d6dcbf3b66981 |
| 出典メモ | uspto-grants-2013_03 |