4-Imidazolidinone, 1-[[1-(3-chloro-4-fluorophenyl)-5-(3-chloro-5-fluorophenyl)-1H-pyrazol-3-yl]carbonyl]- → HCID 44230180、化合物

HRID 1949280ノート

反応式

HRID 1949280 の反応式
ClC1C=C(C2N(C3C=CC=C(Cl)C=3)N=C(C(O)=O)C=2)C=C(F)C=1.[Cl:24][C:25]1[CH:26]=[C:27]([N:32]2[C:36]([C:37]3[CH:42]=[C:41]([F:43])[CH:40]=[C:39]([Cl:44])[CH:38]=3)=[CH:35][C:34]([C:45]([N:47]3[CH2:51][C:50](=[O:52])[NH:49][CH2:48]3)=[O:46])=[N:33]2)[CH:28]=[CH:29][C:30]=1F>>[Cl:44][C:39]1[CH:38]=[C:37]([C:36]2[N:32]([C:27]3[CH:28]=[CH:29][CH:30]=[C:25]([Cl:24])[CH:26]=3)[N:33]=[C:34]([C:45]([N:47]3[CH2:51][C:50](=[O:52])[NH:49][CH2:48]3)=[O:46])[CH:35]=2)[CH:42]=[C:41]([F:43])[CH:40]=1

参加物

3

反応物 2

HCID 442301814-Imidazolidinone, 1-[[1-(3-chloro-4-fluorophenyl)-5-(3-chloro-5-fluorophenyl)-1H-pyrazol-3-yl]carbonyl]-HCID 58277390HCID 58277390、化合物

生成物 1

HCID 44230180HCID 44230180、化合物

実験手順

The preparation of the title compound takes place starting from the compound of Example 72A in analogy to the synthesis of the compound of Example 1. 50 mg (84% of theory) of the title compound are obtained.

出典と根拠

ORDレコード
ord-6eca6c7a952847028d52a3a91234227b
出典データセット
uspto-grants-2013_03
特許番号
US08399682B2

反応ノート

読み込み中…