化工社化工社 化学情報印刷レポート · 研究参考用
L-Lysine → 7-Amino-2-oxoheptanoic acid
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | L-Lysine | HCID 5962 | — |
| 反応物 | 6-Amino-2-oxohexanoic acid | HCID 439954 | — |
| 生成物 | 7-Amino-2-oxoheptanoic acid | HCID 57485229 | — |
反応手順
In an alternative embodiment, lysine is first converted to 6-amino-2-oxohexanoic acid by an aminotransferase enzyme (EC 2.6.1.x) or a dehydrogenase (EC 1.4.1.x or EC 1.4.3.x). Preferred enzymes are listed in Table 7 and may be engineered to catalyze the desired substrate to product reaction. In a subsequent step, 6-amino-2-oxohexanoic acid is subjected to a carbon elongation enzymatic step to produce 7-amino-2-oxoheptanoic acid.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US08404465B2 |
| 出典データセット | uspto-grants-2013_03 |
| ORD ID | ord-b8f58644838640a4b61f784a02a4b55e |
| 出典メモ | uspto-grants-2013_03 |