Hydrochloric Acid → HCID 66985215、化合物
反応式
[CH3:1][O:2][C:3]1[CH:4]=[C:5]([NH:11][C:12]2[C:13]3[C:23](=[O:24])[NH:22][CH:21]=[CH:20][C:14]=3[N:15]=[C:16](SC)[N:17]=2)[CH:6]=[C:7]([O:9][CH3:10])[CH:8]=1.C([NH:32][CH:33]1[CH2:38][CH2:37][NH:36][CH2:35][CH2:34]1)(OC(C)(C)C)=O.[ClH:39]>O1CCOCC1>[ClH:39].[NH2:32][CH:33]1[CH2:38][CH2:37][N:36]([C:16]2[N:17]=[C:12]([NH:11][C:5]3[CH:4]=[C:3]([O:2][CH3:1])[CH:8]=[C:7]([O:9][CH3:10])[CH:6]=3)[C:13]3[C:23](=[O:24])[NH:22][CH:21]=[CH:20][C:14]=3[N:15]=2)[CH2:35][CH2:34]1参加物
5
実験手順
The title compound (Compound 3; MS m/z: 398 (M+H)+) was prepared as described in Example 1g starting from 4-(3,5-dimethoxyphenylamino)-2-(methylthio)pyrido[4,3-d]pyrimidin-5(6H)-one (40 mg, 0.29 mmol) and 4-(boc-amino) piperidine and treating with 4 N HCl in dioxane (17 mg).