2-Chlorobenzoyl chloride → HCID 23295997、化合物

反応式

[Cl-].[Al+3].[Cl-].[Cl-].[Cl:5][C:6]1[CH:14]=[CH:13][CH:12]=[CH:11][C:7]=1[C:8](Cl)=[O:9].[CH2:15]([C:17]1[CH:22]=[CH:21][CH:20]=[CH:19][C:18]=1[O:23][CH3:24])[CH3:16]>C(Cl)Cl>[Cl:5][C:6]1[CH:14]=[CH:13][CH:12]=[CH:11][C:7]=1[C:8]([C:21]1[CH:20]=[CH:19][C:18]([O:23][CH3:24])=[C:17]([CH2:15][CH3:16])[CH:22]=1)=[O:9]

参加物

実験手順

At ambient temperature, to a stirred solution containing aluminum chloride (20 g, 0.150 mol), 2-chlorobenzoylchloride (19 mL, 0.150 mol) in CH2Cl2 (100 mL) was added dropwise 2-ethylanisole (20.4 g, 0.150 mol). After 4 h, the reaction was diluted with CH2Cl2 (400 mL) washed with aq. KH2PO4 (2×200 mL), brine (1×200 mL), filtered though Celite and concentrated to give 38.82 g (94%) of the title compound. 1H NMR: consistent.