1-(3,5-Dimethoxyphenyl)piperazine → 1-[(5,6-Dimethyl-2-methoxypyridin-3-yl)aminothiocarbonyl]-4-(3,5-dimethoxyphenyl)piperazine

HRID 1956287ノート

反応式

HRID 1956287 の反応式
C1(O[C:8](=[S:20])[NH:9][C:10]2[C:11]([O:18][CH3:19])=[N:12][C:13]([CH3:17])=[C:14]([CH3:16])[CH:15]=2)C=CC=CC=1.[CH3:21][O:22][C:23]1[CH:24]=[C:25]([N:31]2[CH2:36][CH2:35][NH:34][CH2:33][CH2:32]2)[CH:26]=[C:27]([O:29][CH3:30])[CH:28]=1>>[CH3:16][C:14]1[CH:15]=[C:10]([NH:9][C:8]([N:34]2[CH2:33][CH2:32][N:31]([C:25]3[CH:24]=[C:23]([O:22][CH3:21])[CH:28]=[C:27]([O:29][CH3:30])[CH:26]=3)[CH2:36][CH2:35]2)=[S:20])[C:11]([O:18][CH3:19])=[N:12][C:13]=1[CH3:17]

参加物

3

反応物 2

HCID 27362051-(3,5-Dimethoxyphenyl)piperazineHCID 53824458Phenyl N-(5,6-dimethyl-2-methoxypyridin-3-yl)thiocarbamate

生成物 1

HCID 540921251-[(5,6-Dimethyl-2-methoxypyridin-3-yl)aminothiocarbonyl]-4-(3,5-dimethoxyphenyl)piperazine収率 69%

実験手順

Phenyl-N-(5,6-dimethyl-2-methoxypyridin-3-yl)thiocarbamate and 1-(3,5-dimethoxyphenyl)piperazine were reacted by the same way with the example 1 to obtain the titled compound.

出典と根拠

ORDレコード
ord-75dd9ad355b244158fb6e55807f05647
出典データセット
uspto-grants-1998_07
特許番号
US05780472

反応ノート

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