Pyridinium → HCID 19069252、化合物
反応式
[CH:1]1([O:7][C:8]2[CH:15]=[CH:14][C:11]([CH2:12][OH:13])=[CH:10][CH:9]=2)[CH2:6][CH2:5][CH2:4][CH:3]=[CH:2]1.[NH+]1C=CC=CC=1>C(Cl)Cl>[CH:1]1([O:7][C:8]2[CH:9]=[CH:10][C:11]([CH:12]=[O:13])=[CH:14][CH:15]=2)[CH2:6][CH2:5][CH2:4][CH:3]=[CH:2]1参加物
4
実験手順
The alcohol prepared above (4.24 g, 20.7 mmol) was dissolved in 250 mL methylene chloride under an atmosphere of dry nitrogen. Pyridinium chlorochormate (5.62 g, 26.1 mmol) was added over 5 minutes. After stirring at ambient temperature for 72 hours, the mixture was filtered through Celite and concentrated in vacuo. Flash silica gel chromatography eluting with 10% ethyl acetate in hexane afforded 3.25 g (77%) of the title compound.
後処理
- filtrationthe mixture was filtered through Celite
- concentrationconcentrated in vacuo
- washFlash silica gel chromatography eluting with 10% ethyl acetate in hexane
出典と根拠
- ORDレコード
- ord-8fd926940899474bbd0f19a5fede7ff9
- 出典データセット
- uspto-grants-1998_07
- 特許番号
- US05783593
反応ノート
読み込み中…