Water → 1-(Methanesulfonyl)-3-methoxy-5-nitrobenzene
反応式
[CH3:1][S:2]([C:5]1[CH:10]=[C:9]([N+:11]([O-:13])=[O:12])[CH:8]=[C:7]([N+]([O-])=O)[CH:6]=1)(=[O:4])=[O:3].[CH3:17][O-:18].[Na+].O>CO>[CH3:1][S:2]([C:5]1[CH:10]=[C:9]([N+:11]([O-:13])=[O:12])[CH:8]=[C:7]([O:18][CH3:17])[CH:6]=1)(=[O:4])=[O:3]参加物
5
実験手順
To a solution of 1-methylsulfonyl-3,5-dinitro-benzene (2.0 g; 8 mmol) in methanol (15 ml) a solution of sodium methoxide (0.5 g; 10 mmol) in methanol (5 ml) was added. The mixture was refluxed for 2 hours. Water was added and the precipitate washed with a diisopropylether/ethanol mixture. 1.3 g (5.62 mmol; 70% yield) of 1-methylsulfonyl-3-methoxy-5-nitro-benzene were obtained as a yellow solid.
後処理
- temperatureThe mixture was refluxed for 2 hours
- washthe precipitate washed with a diisopropylether/ethanol mixture
出典と根拠
- ORDレコード
- ord-1b0ba32a21fa4c3c90097b6cc6ab2868
- 出典データセット
- uspto-grants-2013_04
- 特許番号
- US08410100B2
反応ノート
読み込み中…