4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-indazole → 2-(1H-indazol-4-yl)-6-((1-methylpiperidin-4-ylidene)methyl)-4-morpholinothieno[3,2-d]pyrimidine

反応式

[CH3:25][C:26]1([CH3:27])[C:28]([CH3:29])([CH3:30])[O:31][B:32]([c:33]2[c:34]3[cH:35][n:36][nH:37][c:38]3[cH:39][cH:40][cH:41]2)[O:42]1.[Cl:1][c:2]1[n:3][c:4]([N:19]2[CH2:20][CH2:21][O:22][CH2:23][CH2:24]2)[c:5]2[c:6]([n:7]1)[cH:8][c:9]([CH:11]=[C:12]1[CH2:13][CH2:14][N:15]([CH3:18])[CH2:16][CH2:17]1)[s:10]2>>[c:2]1(-[c:33]2[c:34]3[cH:35][n:36][nH:37][c:38]3[cH:39][cH:40][cH:41]2)[n:3][c:4]([N:19]2[CH2:20][CH2:21][O:22][CH2:23][CH2:24]2)[c:5]2[c:6]([n:7]1)[cH:8][c:9]([CH:11]=[C:12]1[CH2:13][CH2:14][N:15]([CH3:18])[CH2:16][CH2:17]1)[s:10]2

参加物

反応物 2

HCID 454801864-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-indazole

HCID 866183992-Chloro-6-(1-methyl-piperidin-4-ylidenemethyl)-4-morpholin-4-yl-thieno[3,2-d]pyrimidine

生成物 1

HCID 595929482-(1H-indazol-4-yl)-6-((1-methylpiperidin-4-ylidene)methyl)-4-morpholinothieno[3,2-d]pyrimidine

出典と根拠

ORDレコード: ord-6bcf8f0db037404aa02f25265492e819
出典データセット: Training data from https://doi.org/10.1039/C8SC04228D (6/10)
DOI: 10.1039/C8SC04228D

反応ノート

読み込み中…