Methyl phenyl sulfone → [2,6-Difluoro-4-(4-methylsulfonylphenyl)phenyl]-[2-(pyrrolidin-1-ylmethyl)pyrrolidin-1-yl]methanone

HRID 195949

反応式

[BH:23]([OH:24])[OH:25].[Br:1][c:2]1[cH:3][c:4]([F:22])[c:5]([C:9](=[O:10])[N:11]2[CH:12]([CH2:16][N:17]3[CH2:18][CH2:19][CH2:20][CH2:21]3)[CH2:13][CH2:14][CH2:15]2)[c:6]([F:8])[cH:7]1.[CH3:26][S:27](=[O:28])(=[O:29])[c:30]1[cH:31][cH:32][cH:33][cH:34][cH:35]1>>[c:2]1(-[c:33]2[cH:32][cH:31][c:30]([S:27]([CH3:26])(=[O:28])=[O:29])[cH:35][cH:34]2)[cH:3][c:4]([F:22])[c:5]([C:9](=[O:10])[N:11]2[CH:12]([CH2:16][N:17]3[CH2:18][CH2:19][CH2:20][CH2:21]3)[CH2:13][CH2:14][CH2:15]2)[c:6]([F:8])[cH:7]1