Toluene → 5-chloro-N-({[7-(cyclohexylamino)-6-fluoro-1-isopropyl-4-oxo-1,4-dihydroquinolin-3-yl]amino}carbonyl)thiophene-2-sulfonamide

反応式

[CH2:1]([O:2][C:4]([NH:5][S:6](=[O:7])(=[O:8])[c:9]1[s:10][c:11]([Cl:14])[cH:12][cH:13]1)=[O:15])[CH3:3].[CH3:39][c:40]1[cH:41][cH:42][cH:43][cH:44][cH:45]1.[NH2:16][c:17]1[cH:18][n:19]([CH:36]([CH3:37])[CH3:38])[c:20]2[cH:21][c:22]([NH:29][CH:30]3[CH2:31][CH2:32][CH2:33][CH2:34][CH2:35]3)[c:23]([F:28])[cH:24][c:25]2[c:26]1=[O:27]>>[C:4]([NH:5][S:6](=[O:7])(=[O:8])[c:9]1[s:10][c:11]([Cl:14])[cH:12][cH:13]1)(=[O:15])[NH:16][c:17]1[cH:18][n:19]([CH:36]([CH3:37])[CH3:38])[c:20]2[cH:21][c:22]([NH:29][CH:30]3[CH2:31][CH2:32][CH2:33][CH2:34][CH2:35]3)[c:23]([F:28])[cH:24][c:25]2[c:26]1=[O:27]