Ammonia methanol → 2-amino-N-cyclohexyl-N-methylethanesulfonamide
反応式
[CH:1]1([N:7]([CH3:13])[S:8]([CH:11]=[CH2:12])(=[O:10])=[O:9])[CH2:6][CH2:5][CH2:4][CH2:3][CH2:2]1.CO.[NH3:16]>>[CH:1]1([N:7]([CH3:13])[S:8]([CH2:11][CH2:12][NH2:16])(=[O:10])=[O:9])[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6]1参加物
3
実験手順
Ethenesulfonic acid cyclohexyl-methyl-amide (0.0167 mol) was reacted with a mixture of methanol/ammonia (10 mL) in an autoclave for 16 hours at room temperature, and then the solvent was evaporated. The residue was purified by column chromatography (eluent: 90:10 CH2Cl2:(CH3OH:NH3)). The purest product fractions were collected and the solvent was evaporated to yield the title compound as a residue.
後処理
- customthe solvent was evaporated
- customThe residue was purified by column chromatography (eluent: 90:10 CH2Cl2:(CH3OH:NH3))
- customThe purest product fractions were collected
- customthe solvent was evaporated
出典と根拠
- ORDレコード
- ord-29190851ef6e425c8443a79478759340
- 出典データセット
- uspto-grants-2013_04
- 特許番号
- US08426429B2
反応ノート
読み込み中…