Sodium Bicarbonate → 3-Cyclopropylthiomorpholine 1,1-dioxide
反応式
Cl.[CH:2]1([CH:5]2[CH2:10][S:9](=[O:12])(=[O:11])[CH2:8][CH2:7][NH:6]2)[CH2:4][CH2:3]1.C([O-])(O)=O.[Na+]>CCOC(C)=O>[CH:2]1([CH:5]2[CH2:10][S:9](=[O:11])(=[O:12])[CH2:8][CH2:7][NH:6]2)[CH2:4][CH2:3]1参加物
4
実験手順
A 100 mL round-bottomed flask was charged with 3-cyclopropylthiomorpholine 1,1-dioxide hydrochloride (1.00 g, 4.72 mmol) and 10 mL of EtOAc. To this was added 15 mL of saturated aqueous NaHCO3. After stirring at room temperature for 15 min, the layers were separated. The organics were dried (MgSO4), filtered, and concentrated to give 3-cyclopropylthiomorpholine 1,1-dioxide (0.800 g) as a colorless oil.
後処理
- customthe layers were separated
- dry with materialThe organics were dried (MgSO4)
- filtrationfiltered
- concentrationconcentrated
出典と根拠
- ORDレコード
- ord-7149c6430c64448da0520be0a75968d2
- 出典データセット
- uspto-grants-2013_04
- 特許番号
- US08431563B2
反応ノート
読み込み中…