Hydrochloric Acid → Phenethylamine, alpha,alpha-dimethyl-4-dimethylamino-, dihydrochloride
反応式
[CH3:1][C:2]([NH:14]C(=O)C)([CH3:13])[CH2:3][C:4]1[CH:9]=[CH:8][C:7]([N:10]([CH3:12])[CH3:11])=[CH:6][CH:5]=1.[ClH:18]>O>[ClH:18].[ClH:18].[CH3:12][N:10]([CH3:11])[C:7]1[CH:8]=[CH:9][C:4]([CH2:3][C:2]([NH2:14])([CH3:13])[CH3:1])=[CH:5][CH:6]=1参加物
4
実験手順
A solution of 3.5 of N-[α, α-dimethyl-β-(4-dimethylaminophenyl) ethyl]acetamide in a mixture of 25 ml of water and 25 ml of concentrated hydrochloric acid is reluxed for 16 hours. The solution is then evaporated under reduced pressure and the residue is recrystallized twice from methanol isopropyl ether. Yield: 1.1 g, m.p. 239,5°-240,5°.
後処理
- customThe solution is then evaporated under reduced pressure
- customthe residue is recrystallized twice from methanol isopropyl ether
出典と根拠
- ORDレコード
- ord-b1f78afda1d940c9a3edc7cd831de829
- 出典データセット
- uspto-grants-1976_12
- 特許番号
- US03996381
反応ノート
読み込み中…