HCID 21388874、化合物 → 5-Cyano-2-(4-n-pentyloxyphenyl)-pyrimidine
反応式
Cl[C:2]1[C:7]([C:8]#[N:9])=[CH:6][N:5]=[C:4]([C:10]2[CH:15]=[CH:14][C:13]([O:16][CH2:17][CH2:18][CH2:19][CH2:20][CH3:21])=[CH:12][CH:11]=2)[N:3]=1>[Zn].O1CCOCC1>[C:8]([C:7]1[CH:6]=[N:5][C:4]([C:10]2[CH:15]=[CH:14][C:13]([O:16][CH2:17][CH2:18][CH2:19][CH2:20][CH3:21])=[CH:12][CH:11]=2)=[N:3][CH:2]=1)#[N:9]参加物
4
実験手順
6.0 G. of 4-chloro-5-cyano-2-(4-n-pentyloxyphenyl)-pyrimidine are reacted in 260 ml. of 50% dioxane with 23.0 g. of pre-treated zinc dust and worked up after the reaction in a manner analogous to that described in Example 13. There is obtained 5-cyano-2-(4-n-pentyloxyphenyl)-pyrimidine as colorless crystals having a melting point of 98.0°-98.1° C. (smectic); nematic at 102.1° C; clearing point 133.2° C.
後処理
- customafter the reaction in a manner analogous to