化工社化工社 化学情報印刷レポート · 研究参考用
Tert-Butylamine → (S)-3-(tert-Butylamino)propane-1,2-diol
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Tert-Butylamine | HCID 6385 | — |
| 反応物 | (+)-Glyceraldehyde | HCID 79014 | — |
| 触媒 | Palladium | HCID 23938 | — |
| 溶媒 | Ethanol | HCID 702 | — |
| 生成物 | (S)-3-(tert-Butylamino)propane-1,2-diol | HCID 2733671 | — |
反応手順
30 g of (R)-glyceraldehyde, 36 cc of tert. butylamine in 800 cc of ethanol are hydrogenated over 8 g of 10 % palladium/carbon with H2 for 4 hours, the catalyst is filtered off and the solution is concentrated. (S)-1-tert.butylamino-2,3-dihydroxy-propane is obtained from ethyl acetate/ether (2:1) in the form of crystals having a M.P. of 76°-81°. [α] 20546 = -11.8° (c = 2.0; methanol).
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US03998835 |
| 出典データセット | uspto-grants-1976_12 |
| ORD ID | ord-d34f73f2521a4902bb533a755d4efee5 |
| 出典メモ | uspto-grants-1976_12 |