HCID 21490882、化合物 → HCID 21490887、化合物

HRID 1973893ノート

反応式

HRID 1973893 の反応式
C([O:4][CH2:5][C:6]1[CH:11]=[C:10]([Cl:12])[C:9]([CH2:13][CH2:14][CH2:15][CH3:16])=[C:8]([Cl:17])[N:7]=1)(=O)C>Cl>[OH:4][CH2:5][C:6]1[CH:11]=[C:10]([Cl:12])[C:9]([CH2:13][CH2:14][CH2:15][CH3:16])=[C:8]([Cl:17])[N:7]=1

参加物

3

反応物 1

HCID 21490882HCID 21490882、化合物

生成物 1

HCID 21490887HCID 21490887、化合物

試薬・触媒・溶媒 1

HCID 313Hydrochloric Acid溶媒

実験手順

40 g of 2-acetoxymethyl-4,6-dichloro-5-n-butyl-pyridine in 200 ml of 6 N hydrochloric acid are boiled for 15 hours under reflux. Thereafter the mixture is evaporated to dryness. The residue is taken up in chloroform and extracted by shaking with aqueous potassium carbonate solution. The chloroform solution is dried and evaporated. Fractional distillation yields 2-hydroxymethyl-4,6-dichloro-5-n-butyl-pyridine of boiling point 150°-160° (0.1 mm Hg).

後処理

  1. temperatureunder reflux
  2. customThereafter the mixture is evaporated to dryness
  3. extractionextracted
  4. dry with materialThe chloroform solution is dried
  5. customevaporated
  6. distillationFractional distillation

出典と根拠

ORDレコード
ord-ddf36dc61d3843818b0cdcfe50d241a8
出典データセット
uspto-grants-1976_12
特許番号
US03998955

反応ノート

読み込み中…