Acetone → HCID 21490924、化合物
反応式
[OH:1][CH2:2][C:3]1[CH:8]=[C:7]([O:9][CH3:10])[C:6]([CH2:11][CH2:12][CH2:13][CH3:14])=[CH:5][N:4]=1.[ClH:15].CC(C)=O>CO.CCOCC>[ClH:15].[OH:1][CH2:2][C:3]1[CH:8]=[C:7]([O:9][CH3:10])[C:6]([CH2:11][CH2:12][CH2:13][CH3:14])=[CH:5][N:4]=1参加物
6
実験手順
A solution of 2-hydroxymethyl-4-methoxy-5-n-butyl-pyridine in methanol is adjusted to pH 1 with hydrochloric acid in ether and evaporated to dryness. The water which still adheres is distilled off azeotropically with toluene. The residue thus obtained is digested with acetone and the crystalline product is filtered off. 2-Hydroxymethyl-4-methoxy-5-n-butyl-pyridine hydrochloride of melting point 136°-137° is thus obtained.
後処理
- customevaporated to dryness
- distillationThe water which still adheres is distilled off azeotropically with toluene
- customThe residue thus obtained
- filtrationthe crystalline product is filtered off
出典と根拠
- ORDレコード
- ord-aeed5e8fff4941e58bb877b6c0ed57ff
- 出典データセット
- uspto-grants-1976_12
- 特許番号
- US03998955
反応ノート
読み込み中…