Barium Carbonate → Decahydropyrrolo[3,4-b]pyrrolizin-6-ol
反応式
[OH:1][CH:2]1[CH2:12][N:11]2[CH:4]([CH2:5][CH:6]3[CH:10]2[CH2:9][N:8](C(OCC)=O)[CH2:7]3)[CH2:3]1.C(=O)([O-])[O-].[K+].[K+].C(=O)([O-])[O-].[Ba+2]>O>[OH:1][CH:2]1[CH2:12][N:11]2[CH:4]([CH2:5][CH:6]3[CH:10]2[CH2:9][NH:8][CH2:7]3)[CH2:3]1参加物
5
実験手順
8 g (33.3 mmol) of ethyl 10-hydroxy-1,4-diazatricyclo[6.3.0.02,6 ]undecane-4-carboxylate together with 21 g of Ba(OH)2 X 8H20 are refluxed overnight in 150 ml of water. The mixture is saturated with potassium carbonate, barium carbonate is filtered off with suction, and the mixture is extracted ten times using 100 ml portions of chloroform. The extracts are dried over potassium carbonate, concentrated and distilled.
後処理
- filtrationis filtered off with suction
- extractionthe mixture is extracted ten times
- dry with materialThe extracts are dried over potassium carbonate
- concentrationconcentrated
- distillationdistilled
出典と根拠
- ORDレコード
- ord-f846135195a14766b9c1b6b1716f0435
- 出典データセット
- uspto-grants-1994_02
- 特許番号
- US05284855
反応ノート
読み込み中…