Ammonia → 5-(2-Hydroxyethyl)pyrrolidin-2-one
反応式
CO[CH:3]1[CH2:10][CH2:9][O:8][C:6](=[O:7])[CH2:5][CH2:4]1.[NH3:11]>>[OH:8][CH2:9][CH2:10][CH:3]1[NH:11][C:6](=[O:7])[CH2:5][CH2:4]1参加物
3
実験手順
30 g of 4-methoxycaprolactone were stirred at 330° C. for 1 hour together with 100 g of 25% strength aqueous ammonia in the same manner as described in Example 4. After cooling and depressurizing the autoclave and working up the reaction mixture by distillation, 9.1 g of 5-hydroxyethylpyrrolidone were obtained (34%, based on the 4-methoxycaprolactone employed) and identified by NMR spectroscopy.
後処理
- temperatureAfter cooling
- distillationworking up the reaction mixture by distillation
出典と根拠
- ORDレコード
- ord-ba12bb7415234863b543db073f5e611b
- 出典データセット
- uspto-grants-1994_02
- 特許番号
- US05286875
反応ノート
読み込み中…