2-Propanol, 1-(3,5-dimethylphenoxy)- → 1-(3,5-Dimethylphenoxy)propan-2-one

HRID 1975541

反応式

HRID 1975541 の反応式
[CH3:1][CH:2]([OH:13])[CH2:3][O:4][C:5]1[CH:10]=[C:9]([CH3:11])[CH:8]=[C:7]([CH3:12])[CH:6]=1>C1C2C(=CC=CC=2)CCC1.[Cr].[Cu]>[CH3:12][C:7]1[CH:6]=[C:5]([CH:10]=[C:9]([CH3:11])[CH:8]=1)[O:4][CH2:3][C:2](=[O:13])[CH3:1]

参加物

4

反応物 1

HCID 110739942-Propanol, 1-(3,5-dimethylphenoxy)-

生成物 1

HCID 3088301-(3,5-Dimethylphenoxy)propan-2-one収率 69%

試薬・触媒・溶媒 2

HCID 9833946Chromium, compd. with copper (1:1)触媒HCID 8404Tetralin溶媒

実験手順

5.0 Grams (28 mmol) of 1-methyl-2-(3,5-dimethylphenoxy)ethanol was dissolved in 10 ml of tetralin, and 0.5 g of a copper-chromium catalyst (203 SD, supplied by Nikki Chemical Co., Ltd.) was added. The resultant mixture was stirred under a nitrogen current (0.1 liter/minute) at 210° C. for 8 hours. The catalyst was removed by filtration, and the filtrate was distilled under reduced pressure to give 3.41 g of 1-(3,5-dimethylphenoxy)-2-propanone (boiling point: 88° C./0.35 mmHg, yield 69%).

後処理

  1. customThe catalyst was removed by filtration
  2. distillationthe filtrate was distilled under reduced pressure

出典と根拠

ORDレコード
ord-db33fd0d181f44809e6b01dfded0a332
出典データセット
uspto-grants-1994_02
特許番号
US05286905

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