Water → 1-(3,5-Dimethylphenoxy)-2-propanone oxime

HRID 1975542ノート

反応式

HRID 1975542 の反応式
[CH3:1][C:2]1[CH:3]=[C:4]([CH:10]=[C:11]([CH3:13])[CH:12]=1)[O:5][CH2:6][C:7](=O)[CH3:8].S(O)(O)(=O)=O.[NH2:19][OH:20].C(=O)([O-])O.[Na+].O>C(O)C>[CH3:1][C:2]1[CH:3]=[C:4]([CH:10]=[C:11]([CH3:13])[CH:12]=1)[O:5][CH2:6][C:7](=[N:19][OH:20])[CH3:8]

参加物

6

反応物 4

HCID 962WaterHCID 159255Hydroxylamine, sulfate (1:1)HCID 3088301-(3,5-Dimethylphenoxy)propan-2-oneHCID 516892Sodium Bicarbonate

生成物 1

HCID 731208521-(3,5-Dimethylphenoxy)-2-propanone oxime収率 155.2%

試薬・触媒・溶媒 1

HCID 702Ethanol溶媒

実験手順

10.0 Grams (56 mmol) of 1-(3,5-dimethylphenoxy)-2-propanone was dissolved in 50 ml of ethanol, and 5.53 g (34 mmol) of hydroxylamine sulfate and 5.66 g (67 mmol) of sodium hydrogencarbonate were added. And, the resultant mixture was stirred at room temperature for 4 hours, and 50 ml of water was added. Ethanol was distilled off under reduced pressure, and the resultant solid precipitate was recovered by filtration, washed with water and dried to give 10.2 g of 1-(3,5-dimethylphenoxy)-2-propanone oxime (yield 92%).

後処理

  1. distillationEthanol was distilled off under reduced pressure
  2. filtrationthe resultant solid precipitate was recovered by filtration
  3. washwashed with water
  4. customdried

出典と根拠

ORDレコード
ord-da762cef694e4036a3a81a3b60f80298
出典データセット
uspto-grants-1994_02
特許番号
US05286905

反応ノート

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