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6-Bromohexanamide → 4-[7-(1-Adamantyl)-6-carbamoylpentyloxy-2-naphthyl]benzoic acid
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | 6-Bromohexanamide | HCID 321974 | — |
| 反応物 | Methyl 4-[7-(1-adamantyl)-6-hydroxy-2-naphthyl]benzoate | HCID 22000367 | — |
| 生成物 | 4-[7-(1-Adamantyl)-6-carbamoylpentyloxy-2-naphthyl]benzoic acid | HCID 70230932 | 65.6% |
反応手順
Following the procedure of Example 12(a), but reacting 640 mg (1.55 mmol) of methyl 4-[7-(1-adamantyl)-6-hydroxy-2-naphthyl]benzoate with 450 mg (2.32 mmol) of 6-bromohexanamide, 520 mg (65%) of the expected compound were obtained, which compound had a melting point of 209°-10° C.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US06225328B1 |
| 出典データセット | uspto-grants-2001_05 |
| ORD ID | ord-530f64406b1d4ee588c744046266f245 |
| 出典メモ | uspto-grants-2001_05 |