関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|
| 反応物 | Oct-2-ene | HCID 8126 | — |
| 反応物 | Tetralin | HCID 8404 | — |
| 反応物 | N-Hydroxyphthalimide | HCID 10665 | — |
| 反応物 | 2-Methyl-3-pentyloxirane | HCID 102957 | — |
| 触媒 | Cobalt diacetate | HCID 6277 | — |
| 触媒 | Molybdenum carbonyl (Mo(CO)6) | HCID 98885 | — |
| 溶媒 | Benzonitrile | HCID 7505 | — |
| 生成物 | 1,2,3,4-Tetrahydro-1-naphthalenol | HCID 10723 | 21% |
| 生成物 | 1-Tetralone | HCID 10724 | 43% |
反応手順
A mixture of 4 mmol of 2-octene (a mixture of cis-isomer and trans-isomer), 20 mmol of tetralin, 0.4 mmol of N-hydroxyphthalimide, 0.2 mmol of molybdenum hexacarbonyl, 0.004 mmol of cobalt (II) acetate, 200 mg of Molecular Sieve 4A, and 2 ml of benzonitrile was stirred at 50° C. under an oxygen atmosphere (1 atm) for 20 hours. Gas chromatographic analysis of products in a reaction mixture revealed that 2-octene was converted, at a rate of 82%, into 2,3-epoxyoctane in yield of 72%, and that tetralin was converted, at a rate of 42%, into α-tetralol (yield: 21%) and α-tetralone (yield: 43%).
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 特許番号 | US06229023B1 |
|---|
| 出典データセット | uspto-grants-2001_05 |
|---|
| ORD ID | ord-a36030896dcc435283e753b0a5b7a1fb |
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| 出典メモ | uspto-grants-2001_05 |
|---|
