Triethylamine → 1-{4-[(Prop-2-en-1-yl)oxy]phenyl}-1H-pyrrole-2,5-dione
反応式
[CH2:1]([O:4][C:5]1[CH:10]=[CH:9][C:8]([N:11]2[C:15](=[O:16])[CH2:14][CH:13](Cl)[C:12]2=[O:18])=[CH:7][CH:6]=1)[CH:2]=[CH2:3].C(N(CC)CC)C>ClCCl>[CH2:1]([O:4][C:5]1[CH:6]=[CH:7][C:8]([N:11]2[C:15](=[O:16])[CH:14]=[CH:13][C:12]2=[O:18])=[CH:9][CH:10]=1)[CH:2]=[CH2:3]参加物
4
反応条件
- 温度
- 10 °C
実験手順
N-(4-Allyloxyphenyl)chlorosuccinimide (265.5 g, 1 mole) was dissolved in dichloromethane (1300 ml) and cooled to 10° C. Triethylamine (101 g, 1 mole) was added in 10 min and the reaction was stirred for 10 min. The reaction mixture was washed with 1M hydrochloric acid and dried over sodium sulfate. The organic solvent was removed under reduced pressure and the solid was recrystallized from methanol.
後処理
- washThe reaction mixture was washed with 1M hydrochloric acid
- dry with materialdried over sodium sulfate
- customThe organic solvent was removed under reduced pressure
- customthe solid was recrystallized from methanol
出典と根拠
- ORDレコード
- ord-b6c8e41bcc6b4d1a955957c5e26ebae3
- 出典データセット
- uspto-grants-2001_05
- 特許番号
- US06232430B1
反応ノート
読み込み中…