Tert-Butylamine → t-butyl ammonium (R)-3,4epoxybutyrate

HRID 1977498ノート

反応式

HRID 1977498 の反応式
[C:1]([NH2:5])([CH3:4])([CH3:3])[CH3:2].[OH:6][CH2:7][CH:8](S(C)(=O)=O)[C@@H:9](O)[C:10]([OH:12])=[O:11].O1C[C@H]1CC([O-])=O>>[O:6]1[CH2:7][C@H:8]1[CH2:9][C:10]([O-:12])=[O:11].[C:1]([NH3+:5])([CH3:4])([CH3:3])[CH3:2]

参加物

4

反応物 3

HCID 6385Tert-ButylamineHCID 20656327(R)-3,4-epoxybutyrateHCID 86756701(S)-4-hydroxy-3-methanesulfonyl hydroxybutyric acid

生成物 1

HCID 86756703t-butyl ammonium (R)-3,4epoxybutyrate

実験手順

t-butyl amine (571mg, 7.81mmol) was added to the reacting solution of D2O containing (S)-4-hydroxy-3-methanesulfonyl hydroxybutyric acid, so prepared from Example 3 and stirred at room temperature for 4 hours. The presence of the target t-butyl anmmonium (R)-3,4-epoxybutyrate in a layer of the reacting solution was confirmed by nuclear magnetic resonance.

後処理

  1. customso prepared from Example 3

出典と根拠

ORDレコード
ord-4f40966c17bc44e4a962cca66156c013
出典データセット
uspto-grants-2001_05
特許番号
US06232478B1

反応ノート

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