4-Aminocyclohexanecarboxylic acid → Methyl (1r,4r)-4-aminocyclohexane-1-carboxylate hydrochloride
反応式
[NH2:1][CH:2]1[CH2:7][CH2:6][CH:5]([C:8]([OH:10])=[O:9])[CH2:4][CH2:3]1.[ClH:11].[CH3:12]O>>[ClH:11].[NH2:1][CH:2]1[CH2:7][CH2:6][CH:5]([C:8]([O:10][CH3:12])=[O:9])[CH2:4][CH2:3]1参加物
3
実験手順
To 5.109 g (35.680 mM) of 4-aminocyclohexane-carboxylic acid was added 50 ml of 10% HCl/methanol and the mixture was refluxed overnight. The solvent was then distilled off under reduced pressure and the residue was crystallized from methanol-diethyl ether to provide the title compound.
後処理
- temperaturethe mixture was refluxed overnight
- distillationThe solvent was then distilled off under reduced pressure
- customthe residue was crystallized from methanol-diethyl ether
出典と根拠
- ORDレコード
- ord-aeb2297a17b2433a91c3e467c9acd3bb
- 出典データセット
- uspto-grants-2001_05
- 特許番号
- US06235731B1
反応ノート
読み込み中…