Hydrochloric Acid → HCID 70247330、化合物

HRID 1978418ノート

反応式

HRID 1978418 の反応式
C(OC([N:8]1[CH2:13][CH2:12][CH:11]([CH2:14][NH:15][C:16](=[O:31])[CH:17]=[CH:18][C:19]2[S:29][C:28]3[N:30]4[C:21](=[CH:22][N:23]=[C:24]4[CH:25]=[CH:26][CH:27]=3)[CH:20]=2)[CH2:10][CH2:9]1)=O)(C)(C)C.[ClH:32]>C(O)C>[ClH:32].[ClH:32].[NH:8]1[CH2:13][CH2:12][CH:11]([CH2:14][NH:15][C:16](=[O:31])[CH:17]=[CH:18][C:19]2[S:29][C:28]3[N:30]4[C:21](=[CH:22][N:23]=[C:24]4[CH:25]=[CH:26][CH:27]=3)[CH:20]=2)[CH2:10][CH2:9]1

参加物

4

反応物 2

HCID 313Hydrochloric AcidHCID 70248359HCID 70248359、化合物

生成物 1

HCID 70247330HCID 70247330、化合物

試薬・触媒・溶媒 1

HCID 702Ethanol溶媒

実験手順

To this crude N-[1-(tert-butoxycarbonyl)piperidin-4-ylmethyl]-3-(5-thia-1,8b-diazaacenaphthylen-4-yl)acrylamide was added 1 ml of concentrated hydrochloric acid and the mixture was stirred at room temperature for 0.5 hour. After addition of ethanol, the mixture was stirred and the resulting precipitate was collected and washed serially with ethanol and diethyl ether to provide the title compound.

後処理

  1. stirringthe mixture was stirred
  2. customthe resulting precipitate was collected
  3. washwashed serially with ethanol and diethyl ether

出典と根拠

ORDレコード
ord-373810fc5d264c3893955c649536d98b
出典データセット
uspto-grants-2001_05
特許番号
US06235731B1

反応ノート

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