Hydrochloric Acid → HCID 21994007、化合物

HRID 1978496ノート

反応式

HRID 1978496 の反応式
C(OC([N:8]1[CH2:13][CH2:12][CH:11]([CH2:14][CH2:15][C:16](=[O:31])/[CH:17]=[CH:18]/[C:19]2[S:29][C:28]3[N:30]4[C:21](=[CH:22][N:23]=[C:24]4[CH:25]=[CH:26][CH:27]=3)[CH:20]=2)[CH2:10][CH2:9]1)=O)(C)(C)C.[ClH:32]>C(O)C>[ClH:32].[ClH:32].[NH:8]1[CH2:13][CH2:12][CH:11]([CH2:14][CH2:15][C:16](=[O:31])/[CH:17]=[CH:18]/[C:19]2[S:29][C:28]3[N:30]4[C:21](=[CH:22][N:23]=[C:24]4[CH:25]=[CH:26][CH:27]=3)[CH:20]=2)[CH2:10][CH2:9]1

参加物

4

反応物 2

HCID 313Hydrochloric AcidHCID 21993956HCID 21993956、化合物

生成物 1

HCID 21994007HCID 21994007、化合物

試薬・触媒・溶媒 1

HCID 702Ethanol溶媒

実験手順

To the above crude (E)-5-[1-(tert-butoxycarbonyl)-piperidin-4-yl]-1-(5-thia-1,8b-diazaacenaphthylen-4-yl)-1-penten-3-one was added 5 ml of concentrated hydrochloric acid and the mixture was stirred at room temperature for 15 minutes. To this reaction mixture was added ethanol, followed by stirring, and the resulting precipitate was recovered by filtration and rinsed serially with ethanol and diethyl ether to provide the title compound.

後処理

  1. stirringby stirring
  2. filtrationthe resulting precipitate was recovered by filtration
  3. washrinsed serially with ethanol and diethyl ether

出典と根拠

ORDレコード
ord-b8d82418373b46a2af9812f860e7a1a3
出典データセット
uspto-grants-2001_05
特許番号
US06235731B1

反応ノート

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