Hydrochloric Acid → HCID 21993711、化合物

HRID 1978500ノート

反応式

HRID 1978500 の反応式
C(OC([N:8]1[CH2:13][CH2:12][CH:11]([CH2:14][S:15](/[CH:18]=[CH:19]/[C:20]2[S:30][C:29]3[N:31]4[C:22](=[CH:23][N:24]=[C:25]4[CH:26]=[CH:27][CH:28]=3)[CH:21]=2)(=[O:17])=[O:16])[CH2:10][CH2:9]1)=O)(C)(C)C.[ClH:32]>C(O)C>[ClH:32].[ClH:32].[NH:8]1[CH2:13][CH2:12][CH:11]([CH2:14][S:15](/[CH:18]=[CH:19]/[C:20]2[S:30][C:29]3[N:31]4[C:22](=[CH:23][N:24]=[C:25]4[CH:26]=[CH:27][CH:28]=3)[CH:21]=2)(=[O:17])=[O:16])[CH2:10][CH2:9]1

参加物

4

反応物 2

HCID 313Hydrochloric AcidHCID 86756772HCID 86756772、化合物

生成物 1

HCID 21993711HCID 21993711、化合物

試薬・触媒・溶媒 1

HCID 702Ethanol溶媒

実験手順

To the above crude (E)-4-[2-[1-(tert-butoxycarbon-yl)piperidin-4-ylmethanesulfonyl]vinyl]-5-thia-1,8b-diazaacenaphthylene was added 3 ml of concentrated hydrochloric acid, and the mixture was stirred at room temperature for 10 minutes. To this reaction mixture was added ethanol, and the resulting precipitate was recovered by filtration and rinsed serially with ethanol and diethyl ether to provide the title compound.

後処理

  1. filtrationthe resulting precipitate was recovered by filtration
  2. washrinsed serially with ethanol and diethyl ether

出典と根拠

ORDレコード
ord-9c1b6533d2bb474ebdcd268d739f565c
出典データセット
uspto-grants-2001_05
特許番号
US06235731B1

反応ノート

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