化工社化工社 化学情報印刷レポート · 研究参考用
2-Bromopropane → alpha-Isopropyl-3,5-dimethoxyphenylacetonitrile
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | 2-Bromopropane | HCID 6358 | — |
| 反応物 | Sodium hydride | HCID 24758 | — |
| 反応物 | 3,5-Dimethoxyphenylacetonitrile | HCID 139445 | — |
| 溶媒 | Dimethylformamide | HCID 6228 | — |
| 生成物 | alpha-Isopropyl-3,5-dimethoxyphenylacetonitrile | HCID 14183624 | — |
反応手順
This is prepared by reacting a solution of 2-(3,5-dimethoxyphenyl)-acetonitrile (4 g, 0.022 mol) in 10 cc of DMF with 2.86 g of isopropyl bromide in 5 cc of DMF, in the presence of a 50% suspension of 1.1 g of sodium hydride in 25 cc of DMF.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US04481207 |
| 出典データセット | uspto-grants-1984_11 |
| ORD ID | ord-d047fe9f29f94682b2e0ae160cb0a8d9 |
| 出典メモ | uspto-grants-1984_11 |