Acetone → HCID 12962350、化合物

HRID 1979879ノート

反応式

HRID 1979879 の反応式
[C:1]1([CH:7]2[NH:11][CH2:10][CH2:9][S:8]2)[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.CC(C)=O.[Cl:16][CH:17]([Cl:21])[C:18](Cl)=[O:19]>O>[C:1]1([CH:7]2[N:11]([C:18](=[O:19])[CH:17]([Cl:21])[Cl:16])[CH2:10][CH2:9][S:8]2)[CH:2]=[CH:3][CH:4]=[CH:5][CH:6]=1

参加物

5

反応物 3

HCID 180AcetoneHCID 6593Dichloroacetyl chlorideHCID 207062-Phenylthiazolidine

生成物 1

HCID 12962350HCID 12962350、化合物

試薬・触媒・溶媒 1

HCID 962Water溶媒

実験手順

Five (5) grams of 2-phenyl thiazolidine was dissolved in 50 ml. of acetone, 3.1 g. of thiethylamine was added and the mixture stirred in a room temperature water bath, while 4.4 g. of dichloroacetyl chloride was added dropwise. The mixture was allowed to stand for about 30 minutes and then poured into water, extracted with methylene chloride, separated, dried over magnesium sulfate, and the solvent stripped under vacuum. There was obtained a yield of 7.3 g. of an oil, the title compound, ND30 =1.5836.

後処理

  1. additionof thiethylamine was added
  2. extractionextracted with methylene chloride
  3. customseparated
  4. dry with materialdried over magnesium sulfate
  5. customThere was obtained a yield of 7.3 g

出典と根拠

ORDレコード
ord-9e04a2b60641407ca64955548d5ec253
出典データセット
uspto-grants-1984_11
特許番号
US04483706

反応ノート

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