Methylamine → HCID 13376801、化合物
反応式
Cl[C:2]1[C:11]2[CH2:10][CH2:9][CH2:8][CH2:7][C:6]=2[C:5]2=[N:12][N:13]=[N:14][N:4]2[N:3]=1.[CH3:15][NH2:16]>CO>[CH3:15][NH:16][C:2]1[C:11]2[CH2:10][CH2:9][CH2:8][CH2:7][C:6]=2[C:5]2=[N:12][N:13]=[N:14][N:4]2[N:3]=1参加物
4
実験手順
A mixture of 6.0 g of 6-chloro-7,8,9,10-tetrahydrotetrazolo[5,1-a]phthalazine and 125 ml of 40% aqueous methylamine in 15 ml of methanol was heated under reflux for 3 hours. The reaction mixture was then cooled and the crystalline solid present was separated by filtration. It was recrystallized from a mixture of dimethylsulfoxide and water to give 6-methylamino-7,8,9,10-tetrahydrotetrazolo[5,1-a]phthalazine melting at about 318° C.
後処理
- temperaturewas heated
- temperatureunder reflux for 3 hours
- temperatureThe reaction mixture was then cooled
- customthe crystalline solid present was separated by filtration
- customIt was recrystallized from a mixture of dimethylsulfoxide and water
出典と根拠
- ORDレコード
- ord-d6e46d352d6947f8833e014629b24089
- 出典データセット
- uspto-grants-1984_11
- 特許番号
- US04485106
反応ノート
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