Hydrochloric Acid → alpha-Cyano-phenylacetic acid pentachlorophenylester

HRID 1980228

反応式

HRID 1980228 の反応式
[C:1]([CH:3]([C:7]1[CH:12]=[CH:11][CH:10]=[CH:9][CH:8]=1)[C:4]([OH:6])=[O:5])#[N:2].[Cl:13][C:14]1[C:19](O)=[C:18]([Cl:21])[C:17]([Cl:22])=[C:16]([Cl:23])[C:15]=1[Cl:24].O=P(Cl)(Cl)Cl.Cl>C(Cl)(Cl)(Cl)Cl>[Cl:13][C:14]1[C:19]([O:5][C:4](=[O:6])[CH:3]([C:7]2[CH:12]=[CH:11][CH:10]=[CH:9][CH:8]=2)[C:1]#[N:2])=[C:18]([Cl:21])[C:17]([Cl:22])=[C:16]([Cl:23])[C:15]=1[Cl:24]

参加物

6

反応物 4

HCID 313Hydrochloric AcidHCID 992PentachlorophenolHCID 24813Phosphorus oxychlorideHCID 26403alpha-Cyanobenzeneacetic acid

生成物 1

HCID 20402417alpha-Cyano-phenylacetic acid pentachlorophenylester

試薬・触媒・溶媒 1

HCID 5943Carbon Tetrachloride溶媒

実験手順

8 g. (0.05 moles) of α-cyanophenylacetic acid, 13 g. (0.05 moles) of pentachlorophenol are mixed together. 4.3 g. (0.05 moles) of phosphoroxychloride are added dropwise. The obtained mixture is heated slowly to 85°-90° C. on an oil-bath and the mixture is kept at this temperature until the HCl evolution ceases. When the reaction is completed, the mixture is cooled to room temperature, and the melt is taken up in 100 ml. of carbon tetrachloride. The solution is washed three times with 30 ml. of water, treated with decolorizing charcoal, dried and evaporated. The product is recrystalized from diisopropyl ether, and crystalline pentachlorophenyl ester is precipitated.

後処理

  1. temperatureThe obtained mixture is heated slowly to 85°-90° C. on an oil-bath
  2. washThe solution is washed three times with 30 ml
  3. additionof water, treated with decolorizing charcoal
  4. customdried
  5. customevaporated
  6. customThe product is recrystalized from diisopropyl ether, and crystalline pentachlorophenyl ester
  7. customis precipitated

出典と根拠

ORDレコード
ord-18a9a5d6942141388dbe7abf23f673ab
出典データセット
uspto-grants-1985_04
特許番号
US04508658

関連ノート

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