Sulfuric Acid → 1-(6-Chloro-2H-chromen-3-yl)-1H-imidazole
反応式
[N:1]1([CH:6]2[CH:11](O)[C:10]3[CH:13]=[C:14]([Cl:17])[CH:15]=[CH:16][C:9]=3[O:8][CH2:7]2)[CH:5]=[CH:4][N:3]=[CH:2]1.S(=O)(=O)(O)O.[NH4+].[OH-]>C(O)(=O)C>[N:1]1([C:6]2[CH2:7][O:8][C:9]3[CH:16]=[CH:15][C:14]([Cl:17])=[CH:13][C:10]=3[CH:11]=2)[CH:5]=[CH:4][N:3]=[CH:2]1参加物
5
実験手順
A solution of 3-(1-imidazolyl)-2,3-dihydro-6-chloro-4H-1-benzopyran-4-ol (5.4 g), acetic acid (81 ml) and sulphuric acid (27 ml) was heated at 80° C. for 8 hours. The solution, poured into ice water (200 ml), neutralized with NH4OH, extracted with CH2Cl2, dried and evaporated to dryness gave 3.9 g of 3-(1-imidazolyl)-6-chloro-2H-1-benzopyran
後処理
- extractionextracted with CH2Cl2
- customdried
- customevaporated to dryness
出典と根拠
- ORDレコード
- ord-cdf38236d2f64d3f9a0d47ec0cf086b2
- 出典データセット
- uspto-grants-1985_04
- 特許番号
- US04510149
反応ノート
読み込み中…